Cohort Profile : The COVID-19 in Pregnancy in Scotland (COPS) dynamic cohort of pregnant women to assess effects of viral and vaccine exposures on pregnancy

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Stock, Sarah J and Carruthers, Jade and Denny, Cheryl and Donaghy, Jack and Goulding, Anna and Hopcroft, Lisa E M and Hopkins, Leanne and Mulholland, Rachel and Agrawal, Utkarsh and Auyeung, Bonnie and Katikireddi, Srinivasa Vittal and McCowan, Colin and Murray, Josie and Robertson, Chris and Sheikh, Aziz and Shi, Ting and Simpson, Colin R and Vasileiou, Eleftheria and Wood, Rachael (2022) Cohort Profile : The COVID-19 in Pregnancy in Scotland (COPS) dynamic cohort of pregnant women to assess effects of viral and vaccine exposures on pregnancy. International Journal of Epidemiology, 51 (5). e245-e255. ISSN 0300-5771 (https://doi.org/10.1093/ije/dyab243)

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Abstract

COVID-19 in Pregnancy in Scotland (COPS) is a new national prospective dynamic cohort that was created to describe the epidemiology of COVID-19 in pregnancy and the effect of SARS-CoV-2 infection on pregnancy outcomes and to investigate the safety and effectiveness of COVID-19 vaccines among pregnant women. The cohort links primary care records to maternity records, national birth and mortality records and other secondary health care data, together with laboratory results and vaccination information, thus providing a robust platform for the study of viral effects and pharmacoepidemiological research. As of 16 September 2021, the dynamic cohort included 123 004 women with 134 070 completed or ongoing pregnancies. Pre-pandemic outcome rates for analyses can be calculated from an approved retrospective extension of the cohort to 1 January 2015. Data are hosted in the Public Health Scotland’s (PHS) trusted research environment (TRE) and access may be granted via an enquiry to [phs.edris@phs.scot].

CORE (COnnecting REpositories)