Are rate and selectivity correlated in iridium-catalysed hydrogen isotope exchange reactions?

Timofeeva, Daria S. and Lindsay, David M. and Kerr, William J. and Nelson, David J. (2021) Are rate and selectivity correlated in iridium-catalysed hydrogen isotope exchange reactions? Catalysis Science and Technology, 11 (16). pp. 5498-5504. ISSN 2044-4753 (https://doi.org/10.1039/D1CY00708D)

[thumbnail of Timofeeva-etal-CST-2021-Are-rate-and-selectivity-correlated-in-iridium-catalysed-hydrogen-isotope]
Preview
 Text. Filename: Timofeeva_etal_CST_2021_Are_rate_and_selectivity_correlated_in_iridium_catalysed_hydrogen_isotope.pdf
Final Published Version
License: Creative Commons Attribution-NonCommercial 4.0 logo
Download (3MB)| Preview

Abstract

Herein we qualitatively examine the relationship between reaction rate and reaction selectivity in iridium-catalysed hydrogen isotope exchange (HIE) reactions directed by Lewis basic functional groups. We have recently developed a directing group scale that allows semi-quantitative predictions of Lewis base directed selectivity in HIE, formally ranking 'relative rates' determined from a structured set of competition experiments. Here, we show that selectivity and rate are in fact not correlated, but that different types of behaviour emerge in competition experiments and that the observed behaviour can be predicted from our established selectivity scale.

ORCID iDs

Timofeeva, Daria S., Lindsay, David M. ORCID logoORCID: https://orcid.org/0000-0003-4498-5094, Kerr, William J. ORCID logoORCID: https://orcid.org/0000-0002-1332-785X and Nelson, David J. ORCID logoORCID: https://orcid.org/0000-0002-9461-5182;
  • Item type:Article
    ID code:77094
    Dates:
    Date
    Event
    21 August 2021
    Published
    9 July 2021
    Published Online
    9 July 2021
    Accepted
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:14 Jul 2021 13:50
    Last modified:02 Dec 2024 04:13
    URI:https://strathprints.strath.ac.uk/id/eprint/77094
CORE (COnnecting REpositories)