Present and future of surface-enhanced Raman scattering

Langer, Judith and Jimenez De Aberasturi, Dorleta and Aizpurua, Javier and Alvarez-Puebla, Ramon A. and Auguié, Baptiste and Baumberg, Jeremy J. and Bazan, Guillermo C. and Bell, Steven E.J. and Boisen, Anja and Brolo, Alexandre G. and Choo, Jaebum and Cialla-May, Dana and Deckert, Volker and Fabris, Laura and Faulds, Karen and García De Abajo, F. Javier and Goodacre, Royston and Graham, Duncan and Haes, Amanda J. and Haynes, Christy L. and Huck, Christian and Itoh, Tamitake and Käll, Mikael and Kneipp, Janina and Kotov, Nicholas A. and Kuang, Hua and Le Ru, Eric C. and Lee, Hiang Kwee and Li, Jian Feng and Ling, Xing Yi and Maier, Stefan A. and Mayerhöfer, Thomas and Moskovits, Martin and Murakoshi, Kei and Nam, Jwa Min and Nie, Shuming and Ozaki, Yukihiro and Pastoriza-Santos, Isabel and Perez-Juste, Jorge and Popp, Juergen and Pucci, Annemarie and Reich, Stephanie and Ren, Bin and Schatz, George C. and Shegai, Timur and Schlücker, Sebastian and Tay, Li Lin and Thomas, K. George and Tian, Zhong Qun and Van Duyne, Richard P. and Vo-Dinh, Tuan and Wang, Yue and Willets, Katherine A. and Xu, Chuanlai and Xu, Hongxing and Xu, Yikai and Yamamoto, Yuko S. and Zhao, Bing and Liz-Marzán, Luis M. (2020) Present and future of surface-enhanced Raman scattering. ACS Nano, 14 (1). pp. 28-117. ISSN 1936-0851 (

[thumbnail of Langer-etal-ACS-Nano-2019-Present-and-future-of-surface-enhanced-raman-scattering]
Text. Filename: Langer_etal_ACS_Nano_2019_Present_and_future_of_surface_enhanced_raman_scattering.pdf
Final Published Version
License: Other

Download (8MB)| Preview


The discovery of the enhancement of Raman scattering by molecules adsorbed on nanostructured metal surfaces is a landmark in the history of spectroscopic and analytical techniques. Significant experimental and theoretical effort has been directed toward understanding the surface-enhanced Raman scattering (SERS) effect and demonstrating its potential in various types of ultrasensitive sensing applications in a wide variety of fields. In the 45 years since its discovery, SERS has blossomed into a rich area of research and technology, but additional efforts are still needed before it can be routinely used analytically and in commercial products. In this Review, prominent authors from around the world joined together to summarize the state of the art in understanding and using SERS and to predict what can be expected in the near future in terms of research, applications, and technological development. This Review is dedicated to SERS pioneer and our coauthor, the late Prof. Richard Van Duyne, whom we lost during the preparation of this article.


Langer, Judith, Jimenez De Aberasturi, Dorleta, Aizpurua, Javier, Alvarez-Puebla, Ramon A., Auguié, Baptiste, Baumberg, Jeremy J., Bazan, Guillermo C., Bell, Steven E.J., Boisen, Anja, Brolo, Alexandre G., Choo, Jaebum, Cialla-May, Dana, Deckert, Volker, Fabris, Laura, Faulds, Karen ORCID logoORCID:, García De Abajo, F. Javier, Goodacre, Royston, Graham, Duncan ORCID logoORCID:, Haes, Amanda J., Haynes, Christy L., Huck, Christian, Itoh, Tamitake, Käll, Mikael, Kneipp, Janina, Kotov, Nicholas A., Kuang, Hua, Le Ru, Eric C., Lee, Hiang Kwee, Li, Jian Feng, Ling, Xing Yi, Maier, Stefan A., Mayerhöfer, Thomas, Moskovits, Martin, Murakoshi, Kei, Nam, Jwa Min, Nie, Shuming, Ozaki, Yukihiro, Pastoriza-Santos, Isabel, Perez-Juste, Jorge, Popp, Juergen, Pucci, Annemarie, Reich, Stephanie, Ren, Bin, Schatz, George C., Shegai, Timur, Schlücker, Sebastian, Tay, Li Lin, Thomas, K. George, Tian, Zhong Qun, Van Duyne, Richard P., Vo-Dinh, Tuan, Wang, Yue, Willets, Katherine A., Xu, Chuanlai, Xu, Hongxing, Xu, Yikai, Yamamoto, Yuko S., Zhao, Bing and Liz-Marzán, Luis M.;