Robotic-assisted 3D bio-printing for repairing bone and cartilage defects through a minimally invasive approach
Lipskas, Julius and Deep, Kamal and Yao, Wei (2019) Robotic-assisted 3D bio-printing for repairing bone and cartilage defects through a minimally invasive approach. Scientific Reports, 9 (1). 3746. ISSN 2045-2322
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Abstract
There is an unmet need for new techniques and methods of healing critical size tissue defects, by further reduction of invasiveness in implant, cell and tissue-based surgery. This paper presents the development of a new regenerative medicine that combines 3D bio-printing and robotic-assisted minimally invasive surgery techniques to meet this need. We investigated the feasibility of Remote Centre of Motion (RCM) and viscous material extrusion 3D printing. A hypothetical, intra-articular, regenerative medicine-based treatment technique for focal cartilage defects of the knee was used as a potential example of the application of 3D printing in vivo. The results of this study suggest, that RCM mechanism is feasible with viscous material extrusion 3D printing processes, without a major trade-off in imprint quality. The achieved printing accuracy at an average dimensional error of 0.06±0.14mm in this new modality of 3D printing is comparable to those described in literature for other types of bioprinting. Robotic assisted 3D bio-printing demonstrated here is a viable option for focal cartilage defect restoration.
Creators(s): | Lipskas, Julius, Deep, Kamal and Yao, Wei; | Item type: | Article |
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ID code: | 66578 |
Keywords: | 3D bioprinting, cartilage defects, focal cartilage, Remote Centre of Motion (RCM), printing accuracy, Bioengineering, Biomedical Engineering |
Subjects: | Technology > Engineering (General). Civil engineering (General) > Bioengineering |
Department: | Faculty of Engineering > Biomedical Engineering |
Depositing user: | Pure Administrator |
Date deposited: | 15 Jan 2019 15:40 |
Last modified: | 26 Feb 2021 04:27 |
URI: | https://strathprints.strath.ac.uk/id/eprint/66578 |
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