Drug and therapeutics committees in Nigeria : evaluation of scope and functionality

Fadare, Joseph O. and Ogunleye, Olayinka and Obiako, Reginald and Orubu, Samuel and Enwere, Okezie and Ajemigbitse, Adetutu A. and Meyer, Johanna C. and Enato, Ehijie and Massele, Amos and Godman, Brian and Gustafsson, Lars (2018) Drug and therapeutics committees in Nigeria : evaluation of scope and functionality. Expert Review of Clinical Pharmacology, 11 (12). pp. 1255-1262. ISSN 1751-2441 (https://doi.org/10.1080/17512433.2018.1549488)

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Abstract

Introduction: Inappropriate use of medicines remains a problem, with consequences including increasing adverse drug reactions (ADRs) and prolonged hospitalizations. The Essential Medicines List and Drug and Therapeutics Committees (DTCs) are accepted initiatives to promote the rational use of medicines. However, little is known about DTC activities in Nigeria, the most populous African country. Areas covered: A cross-sectional questionnaire-based study was conducted among senior pharmacists, consultant physicians and clinical pharmacologists in 12 leading tertiary healthcare facilities across Nigeria. Expert commentary: Six (50%, 6/12) healthcare facilities had existing DTCs with three (50%) having a sub-committee on antimicrobials. 75% had infection control committees, with presence even in centres without DTCs. Chairpersons and secretaries of the DTCs were predominantly physicians (83.3%) and pharmacists (100%) respectively. Hospital formularies were available in five facilities with DTCs, while one facility without a DTC had an Essential Medicines Committee responsible for developing and updating the hospital formulary. The evaluation of ADRs was undertaken by pharmacovigilance units in nine facilities. Overall, DTCs were present in only half of the surveyed facilities and most were performing their statutory functions sub-optimally. The functioning of DTCs can be improved through government directives and mechanisms for continuous evaluation of activities.

  • Item type:Article
    ID code:66111
    Dates:
    Date
    Event
    30 November 2018
    Published
    14 November 2018
    Accepted
    17 September 2018
    Submitted
    Notes:Copyright © 2018 Informa UK Limited Fadare, J. O., Ogunleye, O., Obiako, R., Orubu, S., Enwere, O., Ajemigbitse, A. A., … Gustafsson, L. L. (2018). Drug and therapeutics committees in Nigeria: evaluation of scope and functionality. Expert Review of Clinical Pharmacology, 11(12), 1255–1262. https://doi.org/10.1080/17512433.2018.1549488
    Subjects:Medicine > Pharmacy and materia medica
    Department:Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
    Depositing user: Pure Administrator
    Date deposited:15 Nov 2018 09:38
    Last modified:02 Dec 2024 01:20
    URI:https://strathprints.strath.ac.uk/id/eprint/66111
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