Does the sphingosine 1-phosphate receptor-1 provide a better or worse prognostic outcome for breast cancer patients?

Pyne, Nigel J. and Pyne, Susan (2018) Does the sphingosine 1-phosphate receptor-1 provide a better or worse prognostic outcome for breast cancer patients? Frontiers in Oncology, 8 (417). pp. 1-3. ISSN 2234-943X (https://doi.org/10.3389/fonc.2018.00417)

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Abstract

Recently, Lei et al., (2018) published an article in Cancer Medicine claiming a survival benefit of sphingosine 1-phosphate (S1P) and sphingosine 1-phosphate receptor 1 (S1P1) expression in breast cancer patients. This controversial study opposes the prevailing view concerning the deleterious role of S1P in cancer. This is discussed in depth in the current opinion article.

ORCID iDs

Pyne, Nigel J. ORCID logoORCID: https://orcid.org/0000-0002-5657-4578 and Pyne, Susan ORCID logoORCID: https://orcid.org/0000-0002-6608-9584;
CORE (COnnecting REpositories)