Picture of model of urban architecture

Open Access research that is exploring the innovative potential of sustainable design solutions in architecture and urban planning...

Strathprints makes available scholarly Open Access content by researchers in the Department of Architecture based within the Faculty of Engineering.

Research activity at Architecture explores a wide variety of significant research areas within architecture and the built environment. Among these is the better exploitation of innovative construction technologies and ICT to optimise 'total building performance', as well as reduce waste and environmental impact. Sustainable architectural and urban design is an important component of this. To this end, the Cluster for Research in Design and Sustainability (CRiDS) focuses its research energies towards developing resilient responses to the social, environmental and economic challenges associated with urbanism and cities, in both the developed and developing world.

Explore all the Open Access research of the Department of Architecture. Or explore all of Strathclyde's Open Access research...

Effect of nanoparticle morphologies on signal strength in photoacoustic sensing

Murdoch, Craig and Kusch, J. and Flockhart, G. M. H. and Graham, D. and Faulds, K. and Uttamchandani, D. (2017) Effect of nanoparticle morphologies on signal strength in photoacoustic sensing. In: Optics + Ultrasound IV, 2017-11-23, University of Strathclyde.

[img]
Preview
Text (Murdoch-etal-OU-2017-Effect-of-nanoparticle-morphologies-on-signal-strength-in-photoacoustic-sensing)
Murdoch_etal_OU_2017_Effect_of_nanoparticle_morphologies_on_signal_strength_in_photoacoustic_sensing.pdf
Accepted Author Manuscript

Download (182kB) | Preview

Abstract

Photoacoustic sensing has the potential to probe to greater depths in tissues compared to optical microscopy. The use of plasmonic nanoparticles can further enhance the photoacoustic signal and the resonances of metallic nanoparticles, e.g. gold, can be aligned with commonly used visible and near-IR laser wavelengths. In addition, surface functionalised nanoparticles can be used to target specifc biomolecules. In this work, we report the synthesis of spherical gold nanoparticles with a plasmonic extinction peak at 532 nm and two sizes of star shaped gold nanoparticles with extinction peaks at 532 nm and 600 nm. The nanoparticles were incorporated into tissue phantoms and the relative performance of the generation of photoacoustic signals from these different nanoparticle morphologies was investigated. At an excitation laser wavelength of 532 nm, we found that the spherical gold nanoparticles generated the greatest photoacoustic response.