Recent developments in organoboron chemistry - old dogs, new tricks

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Fyfe, James W.B. and Watson, Allan J.B. (2017) Recent developments in organoboron chemistry - old dogs, new tricks. Chem, 3 (1). pp. 31-35. ISSN 2451-9294 (https://doi.org/10.1016/j.chempr.2017.05.008)

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Abstract

Organoboron reagents have been synonymous with organic chemistry for over half a century and continue to see widespread application today; for example, classic reactions such as hydroboration and Suzuki-Miyaura cross-coupling are regularly practiced throughout the chemical community. In particular, applications of organoboron compounds have underpinned pharmaceutical and agrochemical development on both discovery and process scales for decades. Although it is noteworthy that these seminal reactions have stood the test of time, continually increasing pressure to improve efficiency in chemical synthesis demands innovation. Over the past few years, through an explosion in the number of new methods for the installation and manipulation of organoboron functional groups, as well as the understanding of their mechanistic operation, organoboron chemistry has risen to this challenge.

ORCID iDs

Fyfe, James W.B. ORCID logoORCID: https://orcid.org/0000-0001-8501-9197 and Watson, Allan J.B.;
CORE (COnnecting REpositories)