A study of diketopiperazines as electron-donor initiators in transition metal-free haloarene-arene coupling

Cumine, Florimond and Zhou, Shengze and Tuttle, Tell and Murphy, John A. (2017) A study of diketopiperazines as electron-donor initiators in transition metal-free haloarene-arene coupling. Organic and Biomolecular Chemistry, 15. 3324 - 3336. ISSN 1477-0520 (https://doi.org/10.1039/C7OB00036G)

[thumbnail of Cumine-etal-OBC-2017-A-study-of-diketopiperazines-as-electron-donor-initiators]
Preview
 Text. Filename: Cumine_etal_OBC_2017_A_study_of_diketopiperazines_as_electron_donor_initiators.pdf
Accepted Author Manuscript
Download (1MB)| Preview

Abstract

Several diketopiperazines have been shown to promote carbon-carbon coupling between benzene and aryl halides in the presence of potassium tert-butoxide and without the assistance of a transition metal catalyst. The structure of the diketopiperazine has an influence on its reductive potential and can help to promote the coupling of the more challenging aryl bromides with benzene.

ORCID iDs

Cumine, Florimond ORCID logoORCID: https://orcid.org/0000-0003-0158-7387, Zhou, Shengze, Tuttle, Tell and Murphy, John A.;
CORE (COnnecting REpositories)