Antibiotic use in acute respiratory infections in under-fives in Uganda : findings and implications

Kibuule, Dan and Hariet Kagoya, Rachel and Godman, Brian (2016) Antibiotic use in acute respiratory infections in under-fives in Uganda : findings and implications. Expert Review of Anti-infective Therapy. pp. 1-27. ISSN 1744-8336

[img]
Preview
Text (Kibuule-Kagoya-Godman-ERAIT2016-antibiotic-use-in-acute-respiratory-infections-in-under-fives)
Kibuule_Kagoya_Godman_ERAIT2016_antibiotic_use_in_acute_respiratory_infections_in_under_fives.pdf
Accepted Author Manuscript

Download (598kB)| Preview

    Abstract

    Objectives: Self-medication with antibiotics among households is common in Uganda. However limited studies evaluating self-purchasing of antibiotics for acute respiratory infections (ARI) in the under-fives. Consequently, the objective was to evaluate patterns of household self-medication with antibiotics in ARI among under-fives in Kampala. Methods: Descriptive cross-sectional observational design. Care takers at households were selected from five divisions of Kampala using the WHO 30-cluster method and interviewed using a standardized questionnaire in June - July 2011. Results: Out of the 200 households, most ARI cases 107 (53.5%; p = 0.322) were inappropriately managed. The prevalence of antibiotic use in ARI was 43% (p < 0.001). Amoxicillin 31.4% and cotrimoxazole (30%) were the most self-medicated antibiotics. Antibiotics use was associated with pneumonia symptoms and access to antibiotics. Conclusions: Household use of antibiotics in ARIs among under-fives is suboptimal. There is an urgent need for guidelines on awareness to reduce self-medication of ARIs in Uganda.