Alkali metal magnesiates : reagents for regioselective double metalations

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O'Hara, Charles (2016) Alkali metal magnesiates : reagents for regioselective double metalations. In: Gordon Research Conference: Organometallic Chemistry. Newport, Rhode Island USA, 2016-07-10 - 2016-07-15, Salve Regina University.

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Abstract

When a sodium (or potassium) reagent is combined with a magnesium one to form a single organometallic bimetallic entity, a special chemistry which cannot be replicated by either individual metal reagent can be obtained. In terms of deprotonative metalation, the mixed alkyl-amido sodium magnesium complex 'Na4Mg2(TMP)6nBu2', where TMP is 2,2,6,6-tetramethylpiperidide, has been shown to be capable of regioselectively deprotonating simple mono-substituted feedstock arenes, some at 2,5 positions and others at 3,5. Here this work is extended to multi-aryl species and heterocycles.

  • Item type:Conference or Workshop Item(Other)
    ID code:56485
    Dates:
    Date
    Event
    15 July 2016
    Published
    27 April 2016
    Accepted
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:24 May 2016 09:04
    Last modified:11 Nov 2024 16:47
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/56485
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