The application of micro-plate dynamics on monitoring cell property

Ma, Xianghong and Wu, Zhangming (2008) The application of micro-plate dynamics on monitoring cell property. In: 15th International Conference on Mechatronics and Machine Vision in Practice, M2VIP 2008, 2008-12-02 - 2008-12-04.

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    The paper presents a novel biosensing method of monitoring cell properties using the information derived from the dynamics of micro-scale plates. Micro cantilevers have been widely applied as mechanical biosensors. In dynamic sense, cantilever is considered as 1 dimensional whereas plate is a 2 dimensional structure. In this paper we provide the first analytical solution to the dynamics of distributed mass loaded microplate in submerged fluid. In a further step, we propose to derive the dynamical infomation of the micro plate and use it to infer the spatial information of the cells when monitoring the cell growth on the plate.