An engineered nano-plasmonic biosensing surface for colorimetric and SERS detection of DNA-hybridization events

Heydari, Esmaeil and Graham, Duncan and Cooper, Jonathan M. and Clark, Alasdair W.; Vo-Dinh, Tuan and Lakowicz, Joseph R., eds. (2015) An engineered nano-plasmonic biosensing surface for colorimetric and SERS detection of DNA-hybridization events. In: Progress in Biomedical Optics and Imaging - Proceedings of SPIE. SPIE, USA. ISBN 9781628414301 (https://doi.org/10.1117/12.2076915)

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Abstract

We report a versatile nanophotonic biosensing platform that enables both colorimetric detection and enhanced Raman spectroscopy detection of molecular binding events. Through the integration of electron-beam lithography, dip-pen-nanolithography and molecular self-assembly, we demonstrate plasmonic nanostructures which change geometry and plasmonic properties in response to molecularly-mediated nanoparticle binding events. These biologically-active nanostructured surfaces hold considerable potential for use as multiplexed sensor platforms for point-of-care diagnostics, and as scaffolds for a new generation of molecularly dynamic metamaterials.

ORCID iDs

Heydari, Esmaeil, Graham, Duncan ORCID logoORCID: https://orcid.org/0000-0002-6079-2105, Cooper, Jonathan M. and Clark, Alasdair W.; Vo-Dinh, Tuan and Lakowicz, Joseph R.
  • Item type:Book Section
    ID code:53894
    Dates:
    Date
    Event
    11 March 2015
    Published
    Notes:Heydari, E., Graham, D., Cooper, J. M., & Clark, A. W. (2015). An engineered nano-plasmonic biosensing surface for colorimetric and SERS detection of DNA-hybridization events. In T. Vo-Dinh, & J. R. Lakowicz (Eds.), Progress in Biomedical Optics and Imaging - Proceedings of SPIE. (Vol. 9340). [93400O-1] SPIE. Copyright 2015 Society of Photo Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic electronic or print reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited. http://dx.doi.org/10.1117/12.2076915
    Subjects:Science > Chemistry
    Department:University of Strathclyde > University of Strathclyde
    Faculty of Science > Pure and Applied Chemistry
    Technology and Innovation Centre > Bionanotechnology
    Depositing user: Pure Administrator
    Date deposited:28 Jul 2015 09:56
    Last modified:11 Nov 2024 15:00
    Related URLs:
    URI:https://strathprints.strath.ac.uk/id/eprint/53894
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