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Discover open research at Strathprints as part of International Open Access Week!

23-29 October 2017 is International Open Access Week. The Strathprints institutional repository is a digital archive of Open Access research outputs, all produced by University of Strathclyde researchers.

Explore recent world leading Open Access research content this Open Access Week from across Strathclyde's many research active faculties: Engineering, Science, Humanities, Arts & Social Sciences and Strathclyde Business School.

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Real-time multimodal imaging of nanoparticle-cell interactions in high-throughput microfluidics

Cunha Matos, C.A. and Millington, O.M. and Wark, A. W. and Zagnoni, M. (2014) Real-time multimodal imaging of nanoparticle-cell interactions in high-throughput microfluidics. In: 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences (MicroTAS 2014). CBM Society, San Diego, CA., pp. 968-970. ISBN 9781634396974

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Abstract

We present an interdisciplinary approach that allows for the evaluation of nanoparticle cytotoxicity at the single-cell level. By combining single-cell microfluidics with nanoparticle chemistry, real-time and high-throughput multimodal imaging of cellular interactions with functionalised gold nanorods was successfully achieved. The integration of such techniques into tools for high-resolution cell monitoring and drug screening has, to the best of our knowledge, not been reported.