Proteinase-activated receptors (PARs)

Cunningham, Margaret Rose and Plevin, Robin; Offermanns, Stefan and Rosenthal, Walter, eds. (2008) Proteinase-activated receptors (PARs). In: Encyclopedia of Molecular Pharmacology. Springer, Berlin, pp. 1019-1023. ISBN 9783540389163 (https://doi.org/10.1007/978-3-540-38918-7_122)

Abstract

Proteinase-activated receptors (PARs) are a unique family of G-protein-coupled receptors (GPCRs) that are activated in response to serine proteinases. There are four PAR family members; PAR-1 through to PAR-4. PAR-1 and PAR-3 respond to thrombin, PAR-2 responds to trypsin, whilst PAR-4 is sensitive to both thrombin- and trypsin-related proteinases.

ORCID iDs

Cunningham, Margaret Rose ORCID: https://orcid.org/0000-0001-6454-8671

Plevin, Robin ORCID: https://orcid.org/0000-0002-7849-1220

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• Item metadata

  Item type:	Book Section
  ID code:	49521
  Dates:	Date Event August 2008 Published
  Subjects:	Medicine > Therapeutics. Pharmacology
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Pure Administrator
  Date deposited:	03 Oct 2014 09:23
  Last modified:	11 Nov 2024 14:57
  Related URLs:	Journal or Publication
  URI:	https://strathprints.strath.ac.uk/id/eprint/49521