Multivalent nanoparticle networks as ultrasensitive enzyme sensors

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De La Rica, Roberto and Fratila, Raluca and Szarpak, Anna and Huskens, Jurriaan and Velders, Aldrik (2011) Multivalent nanoparticle networks as ultrasensitive enzyme sensors. Angewandte Chemie International Edition, 50 (25). 5704–5707. ISSN 1521-3773 (https://doi.org/10.1002/anie.201008189)

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Abstract

As few as 23 enzyme molecules could be detected on the basis of the dispersion of Au nanoparticles in a model bioassay whose sensitivity was boosted by the interplay between multivalent and monovalent supramolecular interactions: a diferrocenyl ligand (red) caused the assembly of nanoparticle clusters; upon its oxidation, a competing monovalent guest molecule (blue) favored the formation of monovalent interactions for more efficient

  • Item type:Article
    ID code:45688
    Dates:
    Date
    Event
    14 June 2011
    Published
    17 May 2011
    Published Online
    Subjects:Science > Physics
    Department:Faculty of Science > Physics
    Depositing user: Pure Administrator
    Date deposited:06 Nov 2013 11:23
    Last modified:11 Nov 2024 10:32
    URI:https://strathprints.strath.ac.uk/id/eprint/45688
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