Biocatalytically triggered co-assembly of two-component core/shell nanofibers
Abul-Haija, Yousef M and Roy, Sangita and Frederix, Pim W J M and Javid, Nadeem and Jayawarna, Vineetha and Ulijn, Rein V (2013) Biocatalytically triggered co-assembly of two-component core/shell nanofibers. Small. (https://doi.org/10.1002/smll.201301668)
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Abstract
For the development of applications and novel uses for peptide nanostructures, robust routes for their surface functionalization, that ideally do not interfere with their self-assembly properties, are required. Many existing methods rely on covalent functionalization, where building blocks are appended with functional groups, either pre- or post-assembly. A facile supramolecular approach is demonstrated for the formation of functionalized nanofibers by combining the advantages of biocatalytic self-assembly and surfactant/gelator co-assembly. This is achieved by enzymatically triggered reconfiguration of free flowing micellar aggregates of pre-gelators and functional surfactants to form nanofibers that incorporate and display the surfactants' functionality at the surface. Furthermore, by varying enzyme concentration, the gel stiffness and supramolecular organization of building blocks can be varied.
ORCID iDs
Abul-Haija, Yousef M ORCID: https://orcid.org/0000-0002-0357-0653, Roy, Sangita, Frederix, Pim W J M, Javid, Nadeem, Jayawarna, Vineetha ORCID: https://orcid.org/0000-0002-2936-6634 and Ulijn, Rein V ORCID: https://orcid.org/0000-0001-7974-3779;-
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Item type: Article ID code: 45073 Dates: DateEvent11 September 2013Published11 September 2013Published Online2013AcceptedNotes: © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. Subjects: Science > Chemistry Department: Faculty of Science > Pure and Applied Chemistry
Faculty of Science > Physics
Technology and Innovation Centre > BionanotechnologyDepositing user: Pure Administrator Date deposited: 08 Oct 2013 09:06 Last modified: 06 Oct 2024 05:10 URI: https://strathprints.strath.ac.uk/id/eprint/45073