Exceptionally strong intermolecular association in hydrophobic DNA minor groove binders and their potential therapeutic consequences

Parkinson, John A and Scott, Fraser J and Suckling, Colin J and Wilson, Gail (2013) Exceptionally strong intermolecular association in hydrophobic DNA minor groove binders and their potential therapeutic consequences. MedChemComm, 4 (7). pp. 1105-1108. (https://doi.org/10.1039/C3MD00071K)

Preview

PDF. Filename: c3md00071k.pdf Final Published Version Download (355kB)| Preview

Abstract

An antibacterial DNA minor groove binder is shown by NOE experiments to self-associate in aqueous solution at temperatures up to 80 C in an anti-parallel, head-to-tail orientation as found in binding to duplex DNA oligomers.

ORCID iDs

Parkinson, John A ORCID: https://orcid.org/0000-0003-4270-6135

Scott, Fraser J ORCID: https://orcid.org/0000-0003-0229-3698

• Share and Export
  

  Simple MetadataEndNoteAtomRDF+N-TriplesRefWorksRIOXX2 XMLMETSMODSOpenURL ContextObject in SpanJSONReferMultiline CSVDublin CoreASCII CitationRIS (EndNote Online, Zotero, Ref manager, etc)HTML CitationRDF+XMLMPEG-21 DIDLBibTeXRDF+N3EP3 XMLOpenURL ContextObjectData Cite XML
• Item metadata

  Item type:	Article
  ID code:	44425
  Dates:	Date Event 2013 Published 20 May 2013 Published Online
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry
  Depositing user:	Pure Administrator
  Date deposited:	31 Jul 2013 15:24
  Last modified:	31 Jan 2025 19:29
  Related URLs:	Scopus publication
  URI:	https://strathprints.strath.ac.uk/id/eprint/44425