Improving the understanding of oligonucleotide–nanoparticle conjugates using DNA-binding fluorophores

Guerrini, Luca and Barrett, Lee and Dougan, Jennifer A. and Faulds, Karen and Graham, Duncan (2013) Improving the understanding of oligonucleotide–nanoparticle conjugates using DNA-binding fluorophores. Nanoscale, 5 (10). pp. 4166-4170. ISSN 2040-3372 (https://doi.org/10.1039/c3nr01197f)

Abstract

A novel fluorescent-based method for characterisation of oligonucleotide-nanoparticle conjugates (ONPCs) is reported. We exploit the ability of the double-stranded DNA-binding dye, SYBR Green I, to develop a powerful analytical tool to investigate the melting properties and hybridisation behavior of ONPCs as well as their corresponding DNA-mediated assemblies.

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• Item metadata

  Item type:	Article
  ID code:	44277
  Dates:	Date Event 21 May 2013 Published 10 April 2013 Published Online
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry Technology and Innovation Centre > Bionanotechnology
  Depositing user:	Pure Administrator
  Date deposited:	03 Jul 2013 11:30
  Last modified:	08 Apr 2024 20:36
  Related URLs:	Scopus publication
  URI:	https://strathprints.strath.ac.uk/id/eprint/44277