Enzymatic optical resolution via acylation-hydrolysis on a solid support

Ulijn, R V and Bisek, N and Flitsch, S L (2003) Enzymatic optical resolution via acylation-hydrolysis on a solid support. Organic and Biomolecular Chemistry, 1 (4). pp. 621-622. ISSN 1477-0520 (https://doi.org/10.1039/b211887d)

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Abstract

By taking advantage of the reversibility of the thermolysin-catalysed amide synthesis-hydrolysis reaction on a solid support, both L,L and L,D diastereoisomers of dipeptides and L-amino acids are accessible in good yields starting from enantiomeric mixtures of amino acids.

ORCID iDs

Ulijn, R V ORCID logoORCID: https://orcid.org/0000-0001-7974-3779, Bisek, N and Flitsch, S L;
  • Item type:Article
    ID code:43947
    Dates:
    Date
    Event
    21 February 2003
    Published
    28 January 2003
    Published Online
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:30 May 2013 11:45
    Last modified:11 Nov 2024 10:25
    URI:https://strathprints.strath.ac.uk/id/eprint/43947
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