New perspectives on the role of sphingosine 1-phosphate in cancer

Pyne, Susan and Pyne, Nigel; Gulbins, Erich and Petrache, Irina, eds. (2013) New perspectives on the role of sphingosine 1-phosphate in cancer. In: Sphingolipids in Disease. Handbook of experimental pharmacology . Springer-Verlag, Vienna, pp. 55-71. ISBN 9783709115107 (https://doi.org/10.1007/978-3-7091-1511-4_3)

Abstract

In this chapter, we review the latest developments concerning the role of sphingosine 1-phosphate (S1P) in cancer. Particular focus is paid to the role of sphingosine kinases 1 and 2, S1P lyase and S1P-dependent signalling networks in both solid tumours and haematological cancer. The potential of this S1P-dependent pathophysiology as a therapeutic target for the treatment of cancer is also discussed.

ORCID iDs

Pyne, Susan ORCID: https://orcid.org/0000-0002-6608-9584

Pyne, Nigel ORCID: https://orcid.org/0000-0002-5657-4578

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  Item type:	Book Section
  ID code:	42722
  Dates:	Date Event 31 March 2013 Published
  Subjects:	Medicine > Pharmacy and materia medica
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Pure Administrator
  Date deposited:	04 Feb 2013 15:56
  Last modified:	11 Nov 2024 14:51
  Related URLs:	Publisher
  URI:	https://strathprints.strath.ac.uk/id/eprint/42722