Formation of SERS active nanoparticle assemblies via specific carbohydrate-protein interactions

Craig, Derek and Simpson, Jonathan and Faulds, Karen and Graham, Duncan (2013) Formation of SERS active nanoparticle assemblies via specific carbohydrate-protein interactions. Chemical Communications, 49 (1). pp. 30-32. ISSN 1359-7345

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Abstract

An on/off SERS aggregation system has been designed to investigate carbohydrate-lectin interactions. Detection of the lectin ConA was achieved at pico molar levels. Discrimination was also demonstrated between two different carbohydrate moieties demonstrating the specific interaction between the carbohydrate and specific protein present.