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Angle-dependent resonance of localized and propagating surface plasmons in microhole arrays for enhanced biosensing

Live, Ludovic S. and Dhawan, Anuj and Gibson, Kirsty F. and Poirier-Richard, Hugo-Pierre and Graham, Duncan and Canva, Michael and Vo-Dinh, Tuan and Masson, Jean-Francois (2012) Angle-dependent resonance of localized and propagating surface plasmons in microhole arrays for enhanced biosensing. Analytical and Bioanalytical Chemistry, 404 (10). pp. 2859-2868. ISSN 1618-2642

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Abstract

The presence of microhole arrays in thin Au films is suited for the excitation of localized and propagating surface plasmon (SP) modes. Conditions can be established to excite a resonance between the localized and propagating SP modes, which further enhanced the local electromagnetic (EM) field. The co-excitation of localized and propagating SP modes depends on the angle of incidence (theta (exc)) and refractive index of the solution interrogated. As a consequence of the enhanced EM field, enhanced sensitivity and an improved response for binding events by about a factor of 3 to 5 was observed with SPR sensors in the Kretschmann configuration for a set of experimental conditions (lambda (SPR), theta (exc), and eta). Thus, microhole arrays can improve sensing applications of SPR based on classical prism-based instrumentation and are suited for SP-coupled spectroscopic techniques.