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Open Access research with a European policy impact...

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EPRC is a leading institute in Europe for comparative research on public policy, with a particular focus on regional development policies. Spanning 30 European countries, EPRC research programmes have a strong emphasis on applied research and knowledge exchange, including the provision of policy advice to EU institutions and national and sub-national government authorities throughout Europe.

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A stereodivergent asymmetric approach to difluorinated aldonic acids

Audouard, Christophe and Barsukov, Igor and Fawcett, John and Griffith, Gerry A and Percy, Jonathan and Pintat, Stephane and Smith, Clive A (2004) A stereodivergent asymmetric approach to difluorinated aldonic acids. Chemical Communications (13). pp. 1526-1527. ISSN 1359-7345

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Abstract

A (bromodifluoromethyl)alkyne has been deployed in a stereoselective route to difluorinated aldonic acid analogues, in which a Sharpless asymmetric dihydroxylation reaction and diastereoisomer separation set the stage for phenyl group oxidation.