Picture of DNA strand

Pioneering chemical biology & medicinal chemistry through Open Access research...

Strathprints makes available scholarly Open Access content by researchers in the Department of Pure & Applied Chemistry, based within the Faculty of Science.

Research here spans a wide range of topics from analytical chemistry to materials science, and from biological chemistry to theoretical chemistry. The specific work in chemical biology and medicinal chemistry, as an example, encompasses pioneering techniques in synthesis, bioinformatics, nucleic acid chemistry, amino acid chemistry, heterocyclic chemistry, biophysical chemistry and NMR spectroscopy.

Explore the Open Access research of the Department of Pure & Applied Chemistry. Or explore all of Strathclyde's Open Access research...

Strathprints

Short, stereoselective syntheses of α-fluoroalkenoate derivatives, α-fluoroenones and α-fluoroenals from HFC-134a

Kanai, M and Percy, Jonathan (2000) Short, stereoselective syntheses of α-fluoroalkenoate derivatives, α-fluoroenones and α-fluoroenals from HFC-134a. Tetrahedron Letters, 41 (14). 2453–2455. ISSN 0040-4039

Full text not available in this repository.Request a copy from the Strathclyde author

Abstract

Readily-available 1,1,1,2-tetrafluoroethane (Klea HFC-134a) can be converted, via a two-pot sequence into a range of Z--fluoroalkenoyl derivatives following addition reactions to aldehydes. Reaction adducts can be processed into enals and enones upon hydride reduction or Grignard reagent addition in high yield.

Item type:Article
ID code:38893
Keywords:Z-α-fluoroalkenoyl, 1,1,1,2-tetrafluoroethane , hydride reduction, reagents, Chemistry, Biochemistry, Organic Chemistry, Drug Discovery
Subjects:Science > Chemistry
Department:Faculty of Science > Pure and Applied Chemistry
Depositing user: Pure Administrator
Date deposited:03 Apr 2012 13:04
Last modified:28 Mar 2018 08:48
URI:https://strathprints.strath.ac.uk/id/eprint/38893
Export data:
CORE (COnnecting REpositories)