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Open Access research with a European policy impact...

The Strathprints institutional repository is a digital archive of University of Strathclyde's Open Access research outputs. Strathprints provides access to thousands of Open Access research papers by Strathclyde researchers, including by researchers from the European Policies Research Centre (EPRC).

EPRC is a leading institute in Europe for comparative research on public policy, with a particular focus on regional development policies. Spanning 30 European countries, EPRC research programmes have a strong emphasis on applied research and knowledge exchange, including the provision of policy advice to EU institutions and national and sub-national government authorities throughout Europe.

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Nucleotide cross-linking induced by photoreactions of novel platinum (IV) azide complexes

Parkinson, J.A. and Muller, P. and Shroder, B. and Kratochwil, N.A. and Coxall, R.A. and Parkin, A. and Parsons, S. and Sadler, P.J. (2003) Nucleotide cross-linking induced by photoreactions of novel platinum (IV) azide complexes. Angewandte Chemie, 42 (3). pp. 335-339.

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Abstract

Visible light irradiation of inert [PtIV(diam(m)ine)(diazide)] complexes leads to reductive elimination of the azide ligands, production of N2, and formation of bifunctional adducts with guanine bases of the type which are lethal to cancer cells.