Effect of 405 nm high-intensity narrow-spectrum light on osteoblast function

Mcdonald, Richard and Maclean, Michelle and Anderson, John and Macgregor, Scott and Grant, Mary (2011) Effect of 405 nm high-intensity narrow-spectrum light on osteoblast function. In: XII eCells & Materials Conference on Implant Infection, 2011-06-23 - 2011-06-25.

[thumbnail of v021supp02a59.pdf] PDF. Filename: v021supp02a59.pdf
Download (43kB)

Abstract

A significant portion of medical devices fail due to acquired infection, with infection rates after arthroplasty surgery between 1-4%, and considerably higher after revision surgery. To reduce the associated costs of infection, a new preventative method is required. High intensity narrow spectrum (HINS) 405 nm light is a new technology shown to have bactericidal effects on a range of medically important bacteria[1]. The effect of HINS-light on osteoblasts and bacteria were investigated to determine the potential of this technology to contribute to infection prevention in operating theatres, during surgery and postoperative dressing changes.

ORCID iDs

Mcdonald, Richard, Maclean, Michelle ORCID logoORCID: https://orcid.org/0000-0001-5750-0397, Anderson, John ORCID logoORCID: https://orcid.org/0000-0003-4151-1619, Macgregor, Scott ORCID logoORCID: https://orcid.org/0000-0002-0808-585X and Grant, Mary ORCID logoORCID: https://orcid.org/0000-0002-7712-404X;