Differential effect of finasteride on the tissue androgen concentrations in benign prostatic hyperplasia

Habib, F K and Ross, M and Tate, R and Chisholm, G D (1997) Differential effect of finasteride on the tissue androgen concentrations in benign prostatic hyperplasia. Clinical Endocrinology, 46 (2). pp. 137-44. ISSN 0300-0664 (https://doi.org/10.1046/j.1365-2265.1997.950908.x)

Abstract

The 5 alpha-reductase inhibitor, finasteride, provides a logical medical treatment for benign prostatic hyperplasia (BPH). However, the effects of chronic finasteride treatment on prostatic androgen levels, 5 alpha-reductase activity and tissue prostatic specific antigen (PSA) have not been studied. We have examined prostate tissue androgen concentrations and 5 alpha-reductase activity of the gland in men with BPH treated with the drug for 3 months.

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• Item metadata

  Item type:	Article
  ID code:	35166
  Dates:	Date Event 1997 Published
  Subjects:	Medicine > Therapeutics. Pharmacology
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Pure Administrator
  Date deposited:	02 Nov 2011 11:02
  Last modified:	12 Dec 2024 02:37
  URI:	https://strathprints.strath.ac.uk/id/eprint/35166