Oxidation of primary amines to ketones

Knowles, Deborah A. and Mathews, Christopher J. and Tomkinson, Nicholas C. O. (2008) Oxidation of primary amines to ketones. Synlett (18). pp. 2769-2772. ISSN 0936-5214 (https://doi.org/10.1055/s-0028-1083541)

Preview

Text. Filename: Knowles_Mathews_Tomkinson_Synlett_2008_Oxidation_of_primary_amines_to_ketones.pdf Accepted Author Manuscript Download (253kB)| Preview

Abstract

A simple method for the oxidn. of primary amines to the corresponding ketones in the presence of both moisture and air is described. Treatment of an amine with benzoyl peroxide in the presence of Cs2CO3, followed by warming of the hydroxylamine product to 50-70° leads directly to the ketone. The method is shown to be effective for both benzylic and aliph. substrates. [on SciFinder(R)]

ORCID iDs

Tomkinson, Nicholas C. O. ORCID: https://orcid.org/0000-0002-5509-0133

• Share and Export
  

  RDF+XMLBibTeXRIOXX2 XMLRDF+N-TriplesJSONDublin CoreAtomSimple MetadataReferMETSHTML CitationASCII CitationOpenURL ContextObjectEndNoteOpenURL ContextObject in SpanMODSMPEG-21 DIDLEP3 XMLData Cite XMLRIS (EndNote Online, Zotero, Ref manager, etc)RDF+N3Multiline CSV
• Item metadata

  Item type:	Article
  ID code:	34166
  Dates:	Date Event 2008 Published
  Subjects:	Science > Chemistry
  Department:	Faculty of Science > Pure and Applied Chemistry
  Depositing user:	Pure Administrator
  Date deposited:	20 Oct 2011 13:32
  Last modified:	11 Nov 2024 09:52
  URI:	https://strathprints.strath.ac.uk/id/eprint/34166