Picture of DNA strand

Pioneering chemical biology & medicinal chemistry through Open Access research...

Strathprints makes available scholarly Open Access content by researchers in the Department of Pure & Applied Chemistry, based within the Faculty of Science.

Research here spans a wide range of topics from analytical chemistry to materials science, and from biological chemistry to theoretical chemistry. The specific work in chemical biology and medicinal chemistry, as an example, encompasses pioneering techniques in synthesis, bioinformatics, nucleic acid chemistry, amino acid chemistry, heterocyclic chemistry, biophysical chemistry and NMR spectroscopy.

Explore the Open Access research of the Department of Pure & Applied Chemistry. Or explore all of Strathclyde's Open Access research...

Strathprints

A multi-component optimisation of experimental parameters for maximising SERS enhancements

Yaffe, Nicola R. and Ingram, Andrew and Graham, Duncan and Blanch, Ewan W. (2009) A multi-component optimisation of experimental parameters for maximising SERS enhancements. Journal of Raman Spectroscopy, 41 (6). pp. 618-623. ISSN 0377-0486

Full text not available in this repository.Request a copy from the Strathclyde author

Abstract

We present a multi-component optimisation strategy for a range of commonly used Ag colloids as surface-enhanced Raman scattering (SERS) spectroscopy substrates. The concentration-dependent interactions of a wide range of parameters, including colloid and aggregating agent species, were considered in order to achieve optimal SERS enhancements. Few papers in the literature discuss the optimisation of these parameters, never mind multi-component optimisation, and suboptimal responses result in SERS not being utilised to its true capabilities. Significant differences in enhancement factor were observed as a consequence of colloid-aggregating agent interactions and these are shown to be analyte specific. Both the cation and anion of the aggregating agent were found to play an important role in the optimisation process. We show that through the optimisation of experimental conditions, the reliability and applicability of SERS can be significantly improved.

Item type:Article
ID code:33666
Keywords:sers, silver colloids, aggregating agents, cysteine, vitamin B-12, dyes, amino acids, silver, nanoparticles, raman spectroscopy , Physical and theoretical chemistry, Spectroscopy, Materials Science(all)
Subjects:Science > Chemistry > Physical and theoretical chemistry
Department:Faculty of Science > Pure and Applied Chemistry
Technology and Innovation Centre > Bionanotechnology
Depositing user: Pure Administrator
Date deposited:17 Oct 2011 13:52
Last modified:29 Mar 2019 03:14
Related URLs:
URI:https://strathprints.strath.ac.uk/id/eprint/33666
Export data:
CORE (COnnecting REpositories)