The fat controller : roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review)

Greaves, Jennifer and Prescott, Gerald R and Gorleku, Oforiwa A and Chamberlain, Luke H (2009) The fat controller : roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review). Molecular Membrane Biology, 26 (1). pp. 67-79.

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Abstract

The attachment of palmitic acid to the amino acid cysteine via thioester linkage (S-palmitoylation) is a common post-translational modification of eukaryotic proteins. In this review, we discuss the role of palmitoylation as a versatile protein sorting signal, regulating protein trafficking between distinct intracellular compartments and the micro-localization of proteins within membranes.

ORCID iDs

Greaves, Jennifer ORCID logoORCID: https://orcid.org/0000-0001-8445-789X, Prescott, Gerald R, Gorleku, Oforiwa A and Chamberlain, Luke H ORCID logoORCID: https://orcid.org/0000-0002-8701-4995;