The fat controller : roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review)

Greaves, Jennifer and Prescott, Gerald R and Gorleku, Oforiwa A and Chamberlain, Luke H (2009) The fat controller : roles of palmitoylation in intracellular protein trafficking and targeting to membrane microdomains (Review). Molecular Membrane Biology, 26 (1). pp. 67-79. (https://doi.org/10.1080/09687680802620351)

Abstract

The attachment of palmitic acid to the amino acid cysteine via thioester linkage (S-palmitoylation) is a common post-translational modification of eukaryotic proteins. In this review, we discuss the role of palmitoylation as a versatile protein sorting signal, regulating protein trafficking between distinct intracellular compartments and the micro-localization of proteins within membranes.

ORCID iDs

Greaves, Jennifer ORCID: https://orcid.org/0000-0001-8445-789X

Chamberlain, Luke H ORCID: https://orcid.org/0000-0002-8701-4995

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  Item type:	Article
  ID code:	32488
  Dates:	Date Event 2009 Published
  Keywords:	protein sorting, lipoylation, membrane microdomains, protein processing, post-translational, protein sorting signals, protein transport, proteins, palmitoylation , lipid rafts, Therapeutics. Pharmacology, Cell Biology, Molecular Biology
  Subjects:	Medicine > Therapeutics. Pharmacology
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Pure Administrator
  Date deposited:	10 Aug 2011 10:45
  Last modified:	24 Mar 2023 10:39
  URI:	https://strathprints.strath.ac.uk/id/eprint/32488