Is there a role for P2 receptors other than the P2X1 subtype in parasympathetic cotransmission in the urinary bladder?

Kennedy, C. (2008) Is there a role for P2 receptors other than the P2X1 subtype in parasympathetic cotransmission in the urinary bladder? Purinergic Signalling, 4. S200-S200. ISSN 1573-9538

Abstract

Parasympathetic nerves innervate the detrusor muscle of the urinary bladder, but a non-cholinergic component ofneurotransmission was recognised over 100 years ago (Langley & Anderson, 1895). Subsequently, ATP was identified asthe cotransmitter with acetylcholine (Kasakov & Burnstock, 1983). Here we have determined the effects of P2X receptorantagonists on the non-cholinergic component of neurotransmission.

ORCID iDs

Kennedy, C. ORCID: https://orcid.org/0000-0001-9661-5437

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• Item metadata

  Item type:	Article
  ID code:	19501
  Dates:	Date Event May 2008 Published
  Keywords:	P2 receptors, P2X1 subtype, parasympathetic, cotransmission, urinary bladder, acetylcholine, Pharmacy and materia medica, Therapeutics. Pharmacology, Cellular and Molecular Neuroscience, Cell Biology, Molecular Biology
  Subjects:	Medicine > Pharmacy and materia medica Medicine > Therapeutics. Pharmacology
  Department:	Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
  Depositing user:	Strathprints Administrator
  Date deposited:	18 May 2010 15:45
  Last modified:	18 Jan 2023 08:54
  Related URLs:	Related item
  URI:	https://strathprints.strath.ac.uk/id/eprint/19501