Comparison of different methods of intracerebral administration of radioiododeoxyuridine for glioma therapy using a rat model

Mairs, R.J. and Wideman, C.L. and Angerson, W.J. and Whateley, T.L. and Reza, M.S. and Reeves, J.R. and Robertson, L.M. and Neshasteh-Riz, A. (2000) Comparison of different methods of intracerebral administration of radioiododeoxyuridine for glioma therapy using a rat model. British Journal of Cancer, 82 (1). pp. 74-80. ISSN 1532-1827

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Abstract

As part of an NHS Executive Trent regional initiative we considered the role and cost-effectiveness of high dose chemotherapy in the treatment of relapsed Hodgkin's disease and non-Hodgkin's lymphoma. The key trials and case series show an additional patient benefit of 0.8-1.1 life years over standard chemotherapy. We estimate incremental cost per life year gained of £12 800-£17 600, which reduces further if long-term benefits are considered. High dose chemotherapy in these conditions is both life-saving and cost-effective.

  • Item type:Article
    ID code:17507
    Dates:
    Date
    Event
    January 2000
    Published
    Notes:Strathprints' policy is to record up to 8 authors per publication, plus any additional authors based at the University of Strathclyde. More authors may be listed on the official publication than appear in the Strathprints' record.
    Keywords:radioiododeoxyuridine, glioma, intracerebral therapy, rat, sustained release, Hodgkin's disease, lymphoma, cost-effectiveness, high dose chemotherapy, transplantation, Neoplasms. Tumors. Oncology (including Cancer), Cancer Research, Oncology
    Subjects:Medicine > Internal medicine > Neoplasms. Tumors. Oncology (including Cancer)
    Department:Unknown Department
    Depositing user: Strathprints Administrator
    Date deposited:22 Apr 2010 08:27
    Last modified:20 Jan 2021 18:24
    URI:https://strathprints.strath.ac.uk/id/eprint/17507
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