Digital twin assisted surgery, concept, opportunities, and challenges

Asciak, Lisa and Kyeremeh, Justicia and Luo, Xichun and Kazakidi, Asimina and Connolly, Patricia and Picard, Frederic and O'Neill, Kevin and Tsaftaris, Sotirios A. and Stewart, Grant D. and Shu, Wenmiao (2025) Digital twin assisted surgery, concept, opportunities, and challenges. npj Digital Medicine, 8. 32. ISSN 2398-6352 (https://doi.org/10.1038/s41746-024-01413-0)

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Abstract

Computer-assisted surgery is becoming essential in modern medicine to accurately plan, guide, and perform surgeries. Similarly, Digital Twin technology is expected to be instrumental in the future of surgery, owing to its capacity to virtually replicate patient-specific interventions whilst providing real-time updates to clinicians. This perspective introduces the term Digital Twin-Assisted Surgery and discusses its potential to improve surgical precision and outcome, along with key challenges for successful clinical translation.

ORCID iDs

Asciak, Lisa ORCID logoORCID: https://orcid.org/0009-0008-8285-198X, Kyeremeh, Justicia, Luo, Xichun ORCID logoORCID: https://orcid.org/0000-0002-5024-7058, Kazakidi, Asimina ORCID logoORCID: https://orcid.org/0000-0001-7124-4123, Connolly, Patricia, Picard, Frederic, O'Neill, Kevin, Tsaftaris, Sotirios A., Stewart, Grant D. and Shu, Wenmiao ORCID logoORCID: https://orcid.org/0000-0002-1220-361X;