Assessment of medication adherence in databases

Sanfélix Gimeno, Gabriel and Mueller, Tanja; Elseviers, Monique and Wettermark, Björn and Benkő, Ria and Bennie, Marion and Gvozdanović, Katarina and Hoffmann, Mikael and Iaru, Irina and Ivanovska, Verica and MacBride-Stewart, Sean and Mueller, Tanja and Poluzzi, Elisabetta and Pont, Lisa and Salvesen Blix, Hege and Sanfélix-Gimeno, Gabriel and Selke, Gisbert and Taxis, Katja and Tomas Petrović, Ana and Trečiokienė, Indrė and Vogler, Sabine, eds. (2024) Assessment of medication adherence in databases. In: Drug Utilization Research. Wiley-Blackwell, Hoboken, NJ, pp. 397-405. ISBN 9781119911685 (https://doi.org/10.1002/9781119911685.ch39)

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Abstract

This chapter focuses on methods for the assessment of medication adherence using electronic databases. It presents a summary of topics including aspects of study design, measurements of adherence, and issues specific to the use of electronic health records. The chapter provides an overview of the strengths and limitations of database research for adherence assessment and also presents existing guidelines for the reporting of database studies. The most appropriate study design for any adherence study depends not only on the data sources available for analyses, but also on the topic area, the research question, and the specific study objectives. Medication adherence researchers are recommended to provide a good description of the adherence construct being measured, the measurement being used, and the results of their sensitivity analyses. The goal of medication adherence research is to develop and propose efficient means of helping prescribers and patients to better manage drug treatments so that they obtain optimal health outcomes.

ORCID iDs

Sanfélix Gimeno, Gabriel and Mueller, Tanja ORCID logoORCID: https://orcid.org/0000-0002-0418-4789; Elseviers, Monique, Wettermark, Björn, Benkő, Ria, Bennie, Marion, Gvozdanović, Katarina, Hoffmann, Mikael, Iaru, Irina, Ivanovska, Verica, MacBride-Stewart, Sean, Mueller, Tanja, Poluzzi, Elisabetta, Pont, Lisa, Salvesen Blix, Hege, Sanfélix-Gimeno, Gabriel, Selke, Gisbert, Taxis, Katja, Tomas Petrović, Ana, Trečiokienė, Indrė and Vogler, Sabine
CORE (COnnecting REpositories)