Risk of winter hospitalisation and death from acute respiratory infections in Scotland : national retrospective cohort study
Shi, Ting and Millington, Tristan and Robertson, Chris and Jeffrey, Karen and Katikireddi, Srinivasa Vittal and McCowan, Colin and Simpson, Colin R and Woolford, Lana and Daines, Luke and Kerr, Steven and Swallow, Ben and Fagbamigbe, Adeniyi and Vallejos, Catalina A and Weatherill, David and Jayacodi, Sandra and Marsh, Kimberley and McMenamin, Jim and Rudan, Igor and Ritchie, Sir Lewis Duthie and Mueller, Tanja and Kurdi, Amanj and Sheikh, Sir Aziz (2024) Risk of winter hospitalisation and death from acute respiratory infections in Scotland : national retrospective cohort study. Journal of the Royal Society of Medicine, 117 (7). pp. 232-246. ISSN 0141-0768 (https://doi.org/10.1177/01410768231223584)
Preview |
Text.
Filename: Shi-etal-JRSM-2023-Risk-of-winter-hospitalisation-and-death-from-acute-respiratory-infections.pdf
Accepted Author Manuscript License: Strathprints license 1.0 Download (715kB)| Preview |
Abstract
Objectives: We undertook a national analysis to characterise and identify risk factors for acute respiratory infections (ARIs) resulting in hospitalisation during the winter period in Scotland. Design: A population-based retrospective cohort analysis. Setting: Scotland. Participants: The study involved 5.4 million residents in Scotland. Main outcome measures: Cox proportional hazard models were used to estimate adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) for the association between risk factors and ARI hospitalisation. Results: Between 1 September 2022 and 31 January 2023, there were 22,284 (10.9% of 203,549 with any emergency hospitalisation) ARI hospitalisations (1759 in children and 20,525 in adults) in Scotland. Compared with the reference group of children aged 6–17 years, the risk of ARI hospitalisation was higher in children aged 3–5 years (aHR = 4.55; 95% CI: 4.11–5.04). Compared with those aged 25–29 years, the risk of ARI hospitalisation was highest among the oldest adults aged ≥80 years (aHR = 7.86; 95% CI: 7.06–8.76). Adults from more deprived areas (most deprived vs. least deprived, aHR = 1.64; 95% CI: 1.57–1.72), with existing health conditions (≥5 vs. 0 health conditions, aHR = 4.84; 95% CI: 4.53–5.18) or with history of all-cause emergency admissions (≥6 vs. 0 previous emergency admissions, aHR = 7.53; 95% CI: 5.48–10.35) were at a higher risk of ARI hospitalisations. The risk increased by the number of existing health conditions and previous emergency admission. Similar associations were seen in children. Conclusions: Younger children, older adults, those from more deprived backgrounds and individuals with greater numbers of pre-existing conditions and previous emergency admission were at increased risk for winter hospitalisations for ARI.
ORCID iDs
Shi, Ting, Millington, Tristan, Robertson, Chris, Jeffrey, Karen, Katikireddi, Srinivasa Vittal, McCowan, Colin, Simpson, Colin R, Woolford, Lana, Daines, Luke, Kerr, Steven, Swallow, Ben, Fagbamigbe, Adeniyi, Vallejos, Catalina A, Weatherill, David, Jayacodi, Sandra, Marsh, Kimberley, McMenamin, Jim, Rudan, Igor, Ritchie, Sir Lewis Duthie, Mueller, Tanja ORCID: https://orcid.org/0000-0002-0418-4789, Kurdi, Amanj ORCID: https://orcid.org/0000-0001-5036-1988 and Sheikh, Sir Aziz;-
-
Item type: Article ID code: 87709 Dates: DateEvent12 February 2024Published12 February 2024Published Online11 December 2023AcceptedSubjects: Medicine > Medicine (General) Department: Faculty of Science > Mathematics and Statistics
Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical SciencesDepositing user: Pure Administrator Date deposited: 21 Dec 2023 14:18 Last modified: 13 Oct 2024 15:18 Related URLs: URI: https://strathprints.strath.ac.uk/id/eprint/87709