Three-dimensional fluid–structure interaction simulation of the Wheatley aortic valve

Oliveira, Hugo L. and Buscaglia, Gustavo C. and Paz, Rodrigo R. and Del Pin, Facundo and Cuminato, José A. and Kerr, Monica and McKee, Sean and Stewart, Iain W. and Wheatley, David J. (2023) Three-dimensional fluid–structure interaction simulation of the Wheatley aortic valve. International Journal for Numerical Methods in Biomedical Engineering, 40 (2). e3792. ISSN 2040-7939 (https://doi.org/10.1002/cnm.3792)

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Abstract

Valvular heart diseases (such as stenosis and regurgitation) are recognized as a rapidly growing cause of global deaths and major contributors to disability. The most effective treatment for these pathologies is the replacement of the natural valve with a prosthetic one. Our work considers an innovative design for prosthetic aortic valves that combines the reliability and durability of artificial valves with the flexibility of tissue valves. It consists of a rigid support and three polymer leaflets which can be cut from an extruded flat sheet, and is referred to hereafter as the Wheatley aortic valve (WAV). As a first step towards the understanding of the mechanical behavior of the WAV, we report here on the implementation of a numerical model built with the ICFD multi-physics solver of the LS-DYNA software. The model is calibrated and validated using data from a basic pulsatile-flow experiment in a water-filled straight tube. Sensitivity to model parameters (contact parameters, mesh size, etc.) and to design parameters (height, material constants) is studied. The numerical data allow us to describe the leaflet motion and the liquid flow in great detail, and to investigate the possible failure modes in cases of unfavorable operational conditions (in particular, if the leaflet height is inadequate). In future work the numerical model developed here will be used to assess the thrombogenic properties of the valve under physiological conditions.

ORCID iDs

Oliveira, Hugo L., Buscaglia, Gustavo C., Paz, Rodrigo R., Del Pin, Facundo, Cuminato, José A., Kerr, Monica ORCID logoORCID: https://orcid.org/0000-0003-2969-5910, McKee, Sean, Stewart, Iain W. ORCID logoORCID: https://orcid.org/0000-0002-4374-9842 and Wheatley, David J.;
  • Item type:Article
    ID code:87555
    Dates:
    Date
    Event
    27 November 2023
    Published
    27 November 2023
    Published Online
    1 November 2023
    Accepted
    10 May 2023
    Submitted
    Notes:Copyright © 2023 Owner. This is the peer reviewed version of the following article: Oliveira, HL, Buscaglia, GC, Paz, RR, Del Pin, F, Cuminato, JA, Kerr, M, McKee, S, Stewart, IW & Wheatley, DJ 2023, 'Three-dimensional fluid–structure interaction simulation of the Wheatley aortic valve', International Journal for Numerical Methods in Biomedical Engineering, which has been published in final form at https://doi.org/10.1002/cnm.3792. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.
    Subjects:Medicine > Biomedical engineering. Electronics. Instrumentation
    Science > Mathematics > Electronic computers. Computer science
    Department:Faculty of Science > Mathematics and Statistics
    Faculty of Engineering > Biomedical Engineering
    Depositing user: Pure Administrator
    Date deposited:11 Dec 2023 11:02
    Last modified:11 Nov 2024 14:09
    URI:https://strathprints.strath.ac.uk/id/eprint/87555
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