Fiber photometry-based investigation of brain function and dysfunction
Byron, Nicole and Sakata, Shuzo (2023) Fiber photometry-based investigation of brain function and dysfunction. Neurophotonics, 11 (S1). S11502. (https://doi.org/10.1117/1.NPh.11.S1.S11502)
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Abstract
Fiber photometry is an optical method to monitor fluorescent signals using a fiber optic cannula. Over the past two decades, together with the development of various genetically encoded biosensors, it has been applied to investigate various types of activity in the central nervous system. This includes not only type-specific neuronal population activity, but also non-neuronal activity and neurotransmitter/neuropeptide signals in awake, freely behaving animals. In this perspective, we summarize the recent development of this technique. After describing common technical pitfalls, we discuss future directions of this powerful approach for investigating brain function and dysfunction.
ORCID iDs
Byron, Nicole and Sakata, Shuzo ORCID: https://orcid.org/0000-0001-6796-411X;-
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Item type: Article ID code: 87020 Dates: DateEvent14 November 2023Published17 October 2023AcceptedSubjects: Medicine > Biomedical engineering. Electronics. Instrumentation Department: Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences Depositing user: Pure Administrator Date deposited: 20 Oct 2023 15:05 Last modified: 11 Nov 2024 14:07 URI: https://strathprints.strath.ac.uk/id/eprint/87020