Metabolic dysregulation and sperm motility in male infertility

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Maurya, Sujata and Kesari, Kavindra Kumar and Roychoudhury, Subhadeep and Kolleboyina, Jayaramulu and Jha, Niraj Kumar and Jha, Saurabh Kumar and Sharma, Ankur and Kumar, Arun and Rathi, Brijesh and Kumar, Dhruv; Kesari, Kavindra Kumar and Roychoudhury, Shubhadeep, eds. (2022) Metabolic dysregulation and sperm motility in male infertility. In: Oxidative Stress and Toxicity in Reproductive Biology and Medicine. Advances in Experimental Medicine and Biology. Advances in Experimental Medicine and Biology, 1358 . Springer, Cham, Switzerland, pp. 257-273. ISBN 9783030893408 (https://doi.org/10.1007/978-3-030-89340-8_12)

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Abstract

Nowadays, about 14% of couples have difficulty in conceiving, and half of the cases are attributed to men. Asthenozoospermia or poor sperm motility is considered as the cause of infertility in males which is most common. Even though energy metabolism is considered the main reason for the etiology of asthenospermia, few attempts are made to determine the pathway of its metabolic potential. Recognition of cellular as well as molecular pathways that lead to reduced sperm motility may lead to the implementation of new therapeutic strategies to eliminate low sperm motility in people with asthenozoospermia. This review article discusses the key causes of decreased sperm motility and some of the muted genes and metabolic causes of the same

ORCID iDs

Maurya, Sujata, Kesari, Kavindra Kumar, Roychoudhury, Subhadeep, Kolleboyina, Jayaramulu, Jha, Niraj Kumar, Jha, Saurabh Kumar, Sharma, Ankur ORCID logoORCID: https://orcid.org/0000-0003-3058-760X, Kumar, Arun, Rathi, Brijesh and Kumar, Dhruv; Kesari, Kavindra Kumar and Roychoudhury, Shubhadeep
CORE (COnnecting REpositories)