A platform for stop-flow gradient generation to investigate chemotaxis

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Xiao, Zuyao and Nsamela, Audrey and Garlan, Benjamin and Simmchen, Juliane (2022) A platform for stop-flow gradient generation to investigate chemotaxis. Angewandte Chemie - International Edition, 61 (21). e202117768. ISSN 1521-3773 (https://doi.org/10.1002/anie.202117768)

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Abstract

The ability of artificial microswimmers to respond to external stimuli and the mechanistical details of their origins belong to the most disputed challenges in interdisciplinary science. Therein, the creation of chemical gradients is technically challenging, because they quickly level out due to diffusion. Inspired by pivotal stopped flow experiments in chemical kinetics, we show that microfluidics gradient generation combined with a pressure feedback loop for precisely controlling the stop of the flows, can enable us to study mechanistical details of chemotaxis of artificial Janus micromotors, based on a catalytic reaction. We find that these copper Janus particles display a chemotactic motion along the concentration gradient in both, positive and negative direction and we demonstrate the mechanical reaction of the particles to unbalanced drag forces, explaining this behaviour.

  • Item type:Article
    ID code:82412
    Dates:
    Date
    Event
    16 May 2022
    Published
    24 March 2022
    Published Online
    13 February 2022
    Accepted
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:22 Sep 2022 09:52
    Last modified:28 Nov 2024 17:10
    URI:https://strathprints.strath.ac.uk/id/eprint/82412
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