Isothermal amplification technology for disease diagnosis

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Boonbanjong, Poramin and Treerattrakoon, Kiatnida and Waiwinya, Wassa and Pitikultham, Piyawat and Japrung, Deanpen (2022) Isothermal amplification technology for disease diagnosis. Biosensors, 12 (9). 677. ISSN 2079-6374 (https://doi.org/10.3390/bios12090677)

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Abstract

Isothermal amplification (IA) is a nucleic acid amplification technology (NAAT) that has contributed significantly to the healthcare system. The combination of NAAT with a suitable detection platform resulted in higher sensitivity, specificity, and rapid disease diagnosis. Traditional NAAT, such as polymerase chain reaction (PCR), is widely applied in the general healthcare system but is rarely accessed in resource-limited hospitals. Some IA methods provide a rapid, sensitive, specific, and simple method for disease diagnosis. However, not all IA techniques have been regularly used in clinical applications because different biomarkers and sample types affect either the enzyme in the IA system or sample preparation. This review focuses on the application of some IA techniques that have been applied in the medical field and have the potential for use at points of care.

  • Item type:Article
    ID code:82095
    Dates:
    Date
    Event
    24 August 2022
    Published
    19 August 2022
    Accepted
    19 July 2022
    Submitted
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:29 Aug 2022 10:06
    Last modified:16 Dec 2024 19:17
    URI:https://strathprints.strath.ac.uk/id/eprint/82095
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