Validation of R-hf risk score for risk stratification in ischemic heart failure patients : a prospective cohort study

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Rajan, Rajesh and Soman, Suman Omana and Al Jarallah, Mohammed and Zhanna, Kobalava and Dashti, Raja and Al Zakwani, Ibrahim and Al Balool, Joud and Tse, Gary and Setiya, Parul and A. Brady, Peter and Al-Saber, Ahmad and Vijayaraghavan, Govindan (2022) Validation of R-hf risk score for risk stratification in ischemic heart failure patients : a prospective cohort study. Annals of Medicine and Surgery, 80. 104333. ISSN 2049-0801 (https://doi.org/10.1016/j.amsu.2022.104333)

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Abstract

Background: The aim of this study was to validate R-heart failure (R-hf) risk score in ischemic heart failure patients. Methods: We prospectively recruited a cohort of 179 ischemic and 107 non-ischemic heart failure patients. This study mainly focused on ischemic heart failure patients. Non-ischemic heart failure patients were included for the purpose of validation of the risk score in various heart failure groups. Patients were stratified in high risk, moderate risk and low risk groups according to R-hf risk score. Results: A total of 179 participants with ischemic heart failure were included. Based on R-hf risk score, 82 had high risk, 50 had moderate risk and 47 had low risk heart failure scores. More than half of the patients having R-hf score of <5 had renal failure (n = 91, 50.8%) and anemia (n = 99, 55.3%). Notably, HFrEF was more prevalent in patients with high risk score (74, 90.2%). Patients with high risk score had significantly higher creatinine (2.63 ± 1.96, p < 0.001), Troponin-T HS (59.9 ± 38.0, p < 0.001) and PRO BNP (17842 ± 6684, p < 0.001) when compared to patients with low and moderate risk score. Patients with low risk score had significantly higher Hb (13.2 ± 1.85, p < 0.001), Albumin (3.69 ± 0.42, p < 0.001) and GFR (90.0 ± 8.04, p < 0.001). A R-hf score of <5 was a significant predictor of mortality in ischemic (OR = 50.34; 95% CI [16.94–194.00, p < 0.001) and non-ischemic (OR = 46.34; 95% CI [12.97–225.39], p < 0.001) heart failure patients. Conclusions: Lower R-hf risk score is a significant predictor of mortality in ischemic and non-ischemic heart failure patients. Risk score can be accessed at https://www.hfriskcalc.in.

ORCID iDs

Rajan, Rajesh, Soman, Suman Omana, Al Jarallah, Mohammed, Zhanna, Kobalava, Dashti, Raja, Al Zakwani, Ibrahim, Al Balool, Joud, Tse, Gary, Setiya, Parul, A. Brady, Peter, Al-Saber, Ahmad ORCID logoORCID: https://orcid.org/0000-0001-9478-0404 and Vijayaraghavan, Govindan;
  • Item type:Article
    ID code:81914
    Dates:
    Date
    Event
    31 August 2022
    Published
    9 August 2022
    Published Online
    31 July 2022
    Accepted
    Subjects:Medicine
    Department:Faculty of Science > Mathematics and Statistics
    Depositing user: Pure Administrator
    Date deposited:18 Aug 2022 12:56
    Last modified:11 Nov 2024 13:35
    URI:https://strathprints.strath.ac.uk/id/eprint/81914
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