Effect of 405nm high-intensity narrow-spectrum light on osteoblast function

McDonald, R. and Maclean, M. and Anderson, J.G. and Macgregor, S.J. and Grant, M.H. (2011) Effect of 405nm high-intensity narrow-spectrum light on osteoblast function. European Cells and Materials, 21 (Suppl.). p. 59. ISSN 1473-2262 (https://www.ecmconferences.org/abstracts/2011/Coll...)

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A significant portion of medical devices fail due to acquired infection, with infection rates after arthroplasty surgery between 1-4%, and considerably higher after revision surgery. To reduce the associated costs of infection, a new preventative method is required. High intensity narrow spectrum (HINS) 405 nm light is a new technology shown to have bactericidal effects on a range of medically important bacteria[1]. The effect of HINS-light on osteoblasts and bacteria were investigated to determine the potential of this technology to contribute to infection prevention in operating theatres, during surgery and postoperative dressing changes.