Unravelling anomalous mass transport in antisolvent crystallisation

Moreno, Irene and McKechnie, David and Lue, Leo and Cardona, Javier (2022) Unravelling anomalous mass transport in antisolvent crystallisation. In: CMAC Annual Open Day 2022, 2022-05-16 - 2022-05-18.

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Antisolvent crystallisation relies on the difference in solubility of a solute in the solvent and the antisolvent to create supersaturation [1]. The mixing process greatly impacts final product properties such as the CSD and the crystal polymorph obtained [2], as they are influenced by local supersaturation values. However, this process is not well understood, leading to unexpected and undesired phenomena such as oiling out or the formation of unwanted crystal phases, as illustrated in Figure 1.


Moreno, Irene, McKechnie, David ORCID logoORCID: https://orcid.org/0000-0002-5749-684X, Lue, Leo ORCID logoORCID: https://orcid.org/0000-0002-4826-5337 and Cardona, Javier ORCID logoORCID: https://orcid.org/0000-0002-9284-1899;

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