Electrochemical monitoring of alcohol in sweat
Biscay, Julien and Findlay, Ewan and Dennany, Lynn (2021) Electrochemical monitoring of alcohol in sweat. Talanta, 224. 121815. ISSN 0039-9140
![]() |
Text (Biscay-etal-Talanta-2020-Electrochemical-monitoring-of-alcohol-in)
Biscay_etal_Talanta_2020_Electrochemical_monitoring_of_alcohol_in.pdf Accepted Author Manuscript Restricted to Repository staff only until 30 October 2021. License: ![]() Download (1MB) | Request a copy from the Strathclyde author |
Abstract
Rapid, periodic monitoring and detection of ethanol (EtOH) after consumption via a non-invasive measurement has been an area of increased research in recent years. Current point-of-care or on-site detection strategies rely on single use sensors which are inadequate for monitoring during a longer period. A low cost, portable and novel approach is developed here for real-time monitoring over several days utilising electrochemical techniques. The sensor shows oxidation of the ethanol in phosphate buffer and artificial sweat using the amperometric response from the application of +0.9 V to the polyaniline modified screen printed electrode using 1 mM EtOH as the averaged amount of EtOH eliminated in sweat after the consumption of one alcoholic beverage. Our enzyme based electrochemical sensor exhibits a qualitative assessment of the presence of EtOH in small volumes (≤40 μL) of 0.1 M sodium bicarbonate and subsequently artificial sweat, with 50 measurements taken daily over 11 days. While quantitative information is not obtained, the sensor system exhibits excellent stability after 3 months’ dried storage in this complex biological matrix in an oxygen free cabinet. This addresses one of the key challenges for enzyme based electrochemical sensors, namely, the ability for real-time monitoring in complex biological matrices. The qualitative response illustrates the potential for this sensor to be exploited by non-experts which suggests the promise for their wider application in next-generation wearable electronics necessary for alcohol monitoring.
Creators(s): |
Biscay, Julien, Findlay, Ewan and Dennany, Lynn ![]() | Item type: | Article |
---|---|
ID code: | 74468 |
Keywords: | electrochemical sensing, alcohol, biological matrices, reusable device, artificial sweat, Chemistry, Chemistry(all) |
Subjects: | Science > Chemistry |
Department: | Faculty of Science > Pure and Applied Chemistry Strategic Research Themes > Health and Wellbeing Strategic Research Themes > Measurement Science and Enabling Technologies |
Depositing user: | Pure Administrator |
Date deposited: | 02 Nov 2020 16:42 |
Last modified: | 21 Jan 2021 12:27 |
URI: | https://strathprints.strath.ac.uk/id/eprint/74468 |
Export data: |