Application of nanoparticles and nanomaterials in thermal ablation therapy of cancer

Ashikbayeva, Zhannat and Tosi, Daniele and Balmassov, Damir and Schena, Emiliano and Saccomandi, Paola and Inglezakis, Vassilis (2019) Application of nanoparticles and nanomaterials in thermal ablation therapy of cancer. Nanomaterials, 9 (9). 1195. ISSN 2079-4991 (

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Cancer is one of the major health issues with increasing incidence worldwide. In spite of the existing conventional cancer treatment techniques, the cases of cancer diagnosis and death rates are rising year by year. Thus, new approaches are required to advance the traditional ways of cancer therapy. Currently, nanomedicine, employing nanoparticles and nanocomposites, offers great promise and new opportunities to increase the efficacy of cancer treatment in combination with thermal therapy. Nanomaterials can generate and specifically enhance the heating capacity at the tumor region due to optical and magnetic properties. The mentioned unique properties of nanomaterials allow inducing the heat and destroying the cancerous cells. This paper provides an overview of the utilization of nanoparticles and nanomaterials such as magnetic iron oxide nanoparticles, nanorods, nanoshells, nanocomposites, carbon nanotubes, and other nanoparticles in the thermal ablation of tumors, demonstrating their advantages over the conventional heating methods.