A mechanistic and cautionary case study on the use of alternating potential in electrochemical reactions

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Wills, Alfie G. and Poole, Darren L. and Alder, Catherine M. and Reid, Marc (2020) A mechanistic and cautionary case study on the use of alternating potential in electrochemical reactions. ChemElectroChem, 7 (13). pp. 2771-2776. ISSN 2196-0216 (https://doi.org/10.1002/celc.202000648)

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Abstract

A mechanistic study on use of alternating potential (i. e. electrode polarity switching) in synthetic organic electrochemical method development using the IKA ElectraSyn 2.0 is described. Unexpected product selectivity challenges revealed that alternating potential facilitated direct, rather than mediated, electrochemical benzylic C−H oxidation of toluene derivatives. Whilst constant potential irrespective of the direction of electrode polarity was expected, our in-depth analysis revealed changes in the magnitude of applied potential with periodic switching of electrode polarity. These findings highlight an equipment engineering concern that is likely to influence and inform optimization strategies for a wide range of synthetic organic electrochemical methods under development.

ORCID iDs

Wills, Alfie G., Poole, Darren L., Alder, Catherine M. and Reid, Marc ORCID logoORCID: https://orcid.org/0000-0003-4394-3132;
  • Item type:Article
    ID code:72978
    Dates:
    Date
    Event
    1 July 2020
    Published
    2 June 2020
    Published Online
    27 May 2020
    Accepted
    Subjects:Science > Chemistry
    Department:Faculty of Science > Pure and Applied Chemistry
    Depositing user: Pure Administrator
    Date deposited:01 Jul 2020 09:12
    Last modified:11 Nov 2024 12:42
    URI:https://strathprints.strath.ac.uk/id/eprint/72978
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