The bioprinting roadmap

Sun, Wei and Starly, Binil and Daly, Andrew C and Burdick, Jason A and Groll, Jürgen and Skeldon, Gregor and Shu, Wenmiao and Sakai, Yasuyuki and Shinohara, Marie and Nishikawa, Masaki and Jang, Jinah and Cho, Dong-Woo and Nie, Minghao and Takeuchi, Shoji and Ostrovidov, Serge and Khademhosseini, Ali and Kamm, Roger D and Mironov, Vladimir and Moroni, Lorenzo and Ozbolat, Ibrahim T (2020) The bioprinting roadmap. Biofabrication, 12 (2). 022002. ISSN 1758-5082

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    Abstract

    This bioprinting roadmap features salient advances in selected applications of the technique and highlights the status of current developments and challenges, as well as envisioned advances in science and technology, to address the challenges to the young and evolving technique. The topics covered in this roadmap encompass the broad spectrum of bioprinting; from cell expansion and novel bioink development to cell/stem cell printing, from organoid-based tissue organization to bioprinting of human-scale tissue structures, and from building cell/tissue/organ-on-a-chip to biomanufacturing of multicellular engineered living systems. The emerging application of printing-in-space and an overview of bioprinting technologies are also included in this roadmap. Due to the rapid pace of methodological advancements in bioprinting techniques and wide-ranging applications, the direction in which the field should advance is not immediately clear. This bioprinting roadmap addresses this unmet need by providing a comprehensive summary and recommendations useful to experienced researchers and newcomers to the field.