Perfusion optimisation for vascular grafts design used in the treatment of aortic disease

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Black, Scott and Ritos, Konstantinos and Maclean, Craig and Brodie, Robbie and Kazakidi, Asimina (2019) Perfusion optimisation for vascular grafts design used in the treatment of aortic disease. In: Terumo Aortic Academic Collaborations Conference, 2019-09-12 - 2019-09-12, University of Strathclyde.

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Abstract

Regions of the aortic arch affected by an aneurysm or dissection may require surgical intervention using vascular grafts, which includes a means of re-perfusing the supra-aortic branch vessels. However, graft configuration to ensure optimal post-surgical perfusion is currently poorly understood. Therefore, enhanced understanding of perfusion in patient-specific cases is critical to improving clinical practice and patient outcomes. In this work, a combination of computational and experimental models of the aortic arch were created to investigate the pre-surgical haemodynamics of the aortic arch, using a coupled 3D-0D numerical framework to simulate a range of downstream conditions, both healthy and pathological.

ORCID iDs

Black, Scott, Ritos, Konstantinos ORCID logoORCID: https://orcid.org/0000-0001-6334-6680, Maclean, Craig, Brodie, Robbie and Kazakidi, Asimina ORCID logoORCID: https://orcid.org/0000-0001-7124-4123;
CORE (COnnecting REpositories)