Trends in medicines procurement by the Brazilian federal government from 2006 to 2013

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Borges Luz, Tatiana Chama and Serpa Osorio-de-Castro, Claudia Garcia and Magarinos-Torres, Rachel and Wettermark, Bjorn (2017) Trends in medicines procurement by the Brazilian federal government from 2006 to 2013. PLoS ONE, 12 (4). pp. 1-13. e0174616.. ISSN 1932-6203 (https://doi.org/10.1371/journal.pone.0174616)

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Abstract

The costs of medicines pose a growing burden on healthcare systems worldwide. A comprehensive understanding of current procurement processes provides strong support for the development of effective policies. This study examined Brazilian Federal Government pharmaceutical procurement data provided by the Integrated System for the Administration of General Services (SIASG) database, from 2006 to 2013. Medicine purchases were aggregated by volume and expenditure for each year. Data on expenditure were adjusted for inflation using the Extended National Consumer Price Index (IPCA) for December 31, 2013. Lorenz distribution curves were used to study the cumulative proportion of purchased therapeutic classes. Expenditure variance analysis was performed to determine the impact of each factor, price and/or volume, on total expenditure variation. Annual expenditure on medicines increased 2.72 times, while the purchased volume of drugs increased 1.99 times. A limited number of therapeutic classes dominated expenditure each year. Drugs for infectious diseases drove the increase in expenditures from 2006 to 2009 but were replaced by antineoplastic and immunomodulating agents beginning in 2010. Immunosuppressants (L04), accounted for one third of purchases since 2010, showing the most substantial growth in expenditures during the period (250-fold increase). The overwhelming price-related increase in expenditures caused by these medicines is bound to have a relevant impact on the sustainability of the pharmaceutical supply system. We observed increasing trends in expenditures, especially in specific therapeutic classes. We propose the development and implementation of better medicine procurement systems, and strategies to allow for monitoring of product price, effectiveness, and safety. This must be done with ongoing assessment of pharmaceutical innovations, therapeutic value and budget impact.

ORCID iDs

Borges Luz, Tatiana Chama ORCID logoORCID: https://orcid.org/0000-0003-1323-3105, Serpa Osorio-de-Castro, Claudia Garcia, Magarinos-Torres, Rachel and Wettermark, Bjorn;
  • Item type:Article
    ID code:71890
    Dates:
    Date
    Event
    7 April 2017
    Published
    12 March 2017
    Accepted
    Notes:Chama Borges Luz T, Garcia Serpa Osorio-de-Castro C, Magarinos-Torres R, Wettermark B (2017) Trends in medicines procurement by the Brazilian federal government from 2006 to 2013. PLoS ONE 12(4): e0174616. https://doi.org/10.1371/journal.pone.0174616
    Subjects:Medicine
    Department:Faculty of Science > Strathclyde Institute of Pharmacy and Biomedical Sciences
    Depositing user: Pure Administrator
    Date deposited:26 Mar 2020 11:06
    Last modified:22 Dec 2024 06:29
    URI:https://strathprints.strath.ac.uk/id/eprint/71890
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